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Department ofBioengineering

Department of Bioengineering

Advance medical and biological frontiers

BIOE 175L Students

Bioengineers create new biomedical technologies that result in smart, efficient, and cost-effective approaches to diagnose and treat human disease.

From developing miniaturized and implantable microfluidic devices and imaging technology for disease diagnosis, to researching how to fight "superbugs" that have become immune to antibiotics, our faculty and staff are at the forefront of bioengineering. They'll mentor you as you work side-by-side with them in their labs.

Our undergraduate program offers three tracks—Biomolecular, Pre-Med, and Medical Device—that prepare you for a wide array of careers, from law to medicine to biotech. Stay an extra year to earn a combined B.S./M.S. degree or join us for your M.S. in Bioengineering and pursue advanced study in medical devices/bioinstrumentation and molecular and cellular bioengineering.


 

Highlights: New Courses and Labs in 2022

The Department of Bioengineering at Santa Clara University is dedicated to continuous improvement of our state-of-art curriculum. New courses and hands-on labs are developed and offered to our students every year, so that our students are building their cutting-edge knowledge with the solid fundamental principles and technical skill sets in the fields of bioengineering.

The department offers the following brand-new courses for 2022, in our brand-new Sobrato Campus for Discovery and Innovation:

BIOE 23. (Spring) Introduction to Bio-Devices (Dr. Ashley Kim)

This course covers the fundamentals of electronic circuits, with particular emphasis on connecting biosensors to analog-to-digital inputs of computers. This lab-based course introduces measuring, modeling, and designing electronic circuits. (4 units)

BIOE 23L. (Spring) Introduction to Bio-Devices Laboratory (Dr. Ashley Kim)

Laboratory for BIOE 23. (1 unit)

BIOE 32L. (Winter) Introduction to Biochemical Engineering Laboratory (Dr. Emily Park)

Laboratory for BIOE 32. (1 unit)

This laboratory course introduces the essential principles and lab techniques in biochemical engineering, including chemical and physical characterization of the biochemical building blocks, characterization of macromolecules such as proteins and DNAs, and analysis of enzyme activity and kinetics.

By taking this course, students should be able to:

  • Explain the critical and specialized biochemical concepts through simplest and fundamental hands-on techniques
  • Train in troubleshooting to evaluate and explain experimental results
  • Practice a meticulous record keeping with accurate and timely entry to lab notebook Communicate effectively, both verbally and in writing, for the results, analysis, and discussions

Key technical elements/skills to be involved include:

Characterization of biochemical building blocks Protein quantification and characterization, including polyacrylamide gel electrophoresis and UV spectrometry using various protein types and conformations Enzymatic activity and Michaelis-Menten kinetics Protein purification using a column chromatography DNA quantification and characterization including Real time quantitative PCR, UV spectrometry, and agarose gel electrophoresis using various forms of DNA materials

BIOE 138/238. (Winter) Medicinal Chemistry and Drug Design I (Dr. Zhiwen Jonathan Zhang)

Small molecule medicines are coming back! In two seminal courses (part I in winter quarter and part II in Spring quarter), students will study the principles of medicinal chemistry in detail, as well as the pharmacology for drug designs. Medicines and their designs in the following categories will be studied in the part I (winter quarter): Human Fluid; drug effecting Acid-Base disorders; neurotransmission (anticholinergics); hormonal systems (growth hormone and androgens); immune system (antihistamines).

The contents of the course are offered at the same level as in pharmacy schools. Students are encouraged to have a strong background in biology, organic chemistry and physiology, but not necessarily about organic synthesis. Students will become familiar with the medicinal terminology and drug names. The course will be beneficial to the students who consider to pursue a career in pharmaceutical industry as well as medical professionals such as MD, PharmD and nurse.

The contents of the course are offered at the same level as in pharmacy schools. Students are encouraged to have a strong background in biology, organic chemistry and physiology, but not necessarily about organic synthesis. Students will become familiar with the medicinal terminology and drug names. The course will be beneficial to the students who consider to pursue a career in pharmaceutical industry as well as medical professionals such as MD, PharmD and nurse. (2 units)

BIOE 139/239. (Spring) Medicinal Chemistry and Drug Design II (Dr. Zhiwen Jonathan Zhang)

This is part II of the seminal courses – Medicinal Chemistry and Drug Design. Students will study the principles of medical chemistry in detail, as well as the pharmacology for drug design. Medicines and their design will be studied in the following categories: Non-steroidal anti-inflammatory drugs (NSAIDs), Glucocorticoids, Thyroid and Thyroid Drugs, Estrogens and Progestins, Adrenergics. On top of the understanding of the principles of drugs, the sequel will be concluded with the “rules” of drug discovery and clinical therapy. (2 units)

BIOE 158/258. (Winter) Soft Biomaterials Characterization (Dr. Maryam Mobed-Miremadi)

This course will cover the fundamental principles of characterization and biodegradation of soft implantable/injectable biomaterials including polymers, hydrogels, liquid crystalline colloids starting with the linkage of microscopic to macroscopic properties and, emphasis on elasticity, adhesion, diffusion and light scattering. Also listed as BIOE 258. (4 units)

BIOE 158L2/258L. (Winter) Soft Biomaterials Characterization Laboratory (Dr. Maryam Mobed-Miremadi)

Laboratory for BIOE 158. Also listed as BIOE 258L. (1 unit)

BIOE 159/259. (Spring) Hard Biomaterials Characterization (Dr. Maryam Mobed-Miremadi)

This course will cover the fundamental principles of characterization and biodegradation of hard biomaterials including bioceramics and metals starting with the linkage of microscopic to macroscopic properties and, emphasis on corrosion, coatings, (nano/micro)-indentation and accelerated implant analysis. Instruction will be complimented by software-enabled simulation of prototyping and driving forces’ analyses. Also listed as BIOE 259. (4 units)

BIOE 159L/259L. (Spring) Hard Biomaterials Characterization Laboratory (Dr. Maryam Mobed-Miremadi)

Laboratory for BIOE 159. Also listed as BIOE 259L. (1 unit)

BIOE 166/216. (Spring) Biosignal and Medical Image Processing (Dr. Yuling Yan)

This course covers the principles and methods of signal and image processing and their applications in biomedical engineering. Various signal and image processing tools, including diagnostic decision-making tools will be introduced at a useful, working depth. (2 units)

Prerequisite: BIOE 162

BIOE 176L. (Winter) Introduction to Biomolecular and cellular engineering II Laboratory (Dr. Emily Park)

Laboratory for BIOE 176. (1 unit)

The laboratory course introduces essential concepts and practical techniques for (1) recombinant antibody production and (2) CRISPR genome editing. Students will experience many technical principles, including synthetic gene design, gene cloning, mammalian cell culture, protein expression and purification, recombinant antibody characterization, CRISPR gene knock-out and knock-in, and single cell analysis by flow cytometry. Each lab session will include hands-on lab experiments in addition to lectures and discussions.

By taking this course, students should be able to:

  • Explain core concepts and techniques required for ‘Recombinant Antibody Engineering’ and 'CRISPR Genome Editing'
  • Train in troubleshooting to evaluate and explain experimental results
  • Practice a meticulous record keeping with accurate and timely entry to lab notebook
  • Communicate effectively, both verbally and in writing, for the results, analysis, and discussions

Key technical elements/skills to be involved include:

  • Recombinant DNA technology for antibody cloning
  • Screening methods for selecting recombinant clones, involving colony PCR and real-time PCR (or agarose gel electrophoresis)
  • Mammalian cell culture and recombinant antibody expression by transfection
  • Purification and characterization of recombinant antibodies, including an affinity column purification and polyacrylamide gel electrophoresis
  • Genome editing using CRISPR by knocking out a human gene in a cell line and knocking in a reporter gene
  • Single cell analysis by flow cytometry
Resources for Prospective Undergraduate Students

Please see below for an overview of our program, alumni profiles, and what our industry advisory board members have to say about SCU Bioengineering.

Natalie Duong_2017 

Natalie Duong

B.S. '17


Nathaniel Girma

B.S. '19


Delaney Gray

B.S. '19


Chloe Herczeg

B.S. '17


Roman Lyman

B.S. '18, M.S. '19


 

Atticus McCoy_2019

Atticus McCoy

B.S. '19


Erik Risa '17, bioengineering

Erik Risa

B.S. '17

Visit our Industry page to read more quotes from our Industry Advisor Board Members like the one below.

Pull quote illustration

"Being a lecturer in the program, advisor to the program, and employer of SCU interns and graduates over many years has given me a unique perspective to the students, graduates, faculty, and university. Santa Clara University (SCU) Bioengineering students are well suited for industry internships and graduates of the program successfully transition into the medical technology and devices industries. In addition to engineering fundamentals, core skills that SCU Bioengineering students learn include CAD, prototyping, introduction to quality and regulatory systems, testing, and biomaterials. Major employers of graduates in the medical device segment for which I am involved include Abbott, Boston Scientific, Intuitive Surgical, Medtronic, Penumbra, and Stryker."

Paul Davison
Chief Operating Officer, Provisio Medical
SCU Bioengineering Advisory Board Chair

Faculty Spotlight

Biao Lu

2020-2021 Researcher of the Year

An M.D. and a Ph.D., Dr. Lu has extensive experience and research expertise in multiple disciplines spanning molecular and cellular biology, biochemistry, genetics, and medicine. His current research focuses on engineering nano-carriers for drug delivery and therapy to treat cancers, hereditary diseases, and viral infections. Since joining SCU in 2015, he has produced more than 20 peer-reviewed, top-cited journal articles and conference papers and recently, as sole PI, was awarded a $410,768 grant from the National Institute of Health, Medical Sciences, to further his pioneering research.

Faculty Spotlight

I. Emre Araci

Dr. Araci's (NSF CAREER Awardee) lab utilizes fluidic physics principles in capillaric devices for wearable biosensing applications. Their ultimate goal is to measure human motion and physiological parameters using easy to use and affordable technologies. In accordance with his research, he teach courses related to microfabrication of microfluidic devices, wearables in clinical applications, and fundamentals of biophotonics.

More Faculty Stories

Staff Spotlight

2020-2021 Staff Member of the Year

Matthew Blanco, Senior Administrative Assistant for Bioengineering was awarded the School of Engineering's Staff Member of the year for his dedication, passion, and hard work within the BioEngineering Department and the School of Engineering.

Current Student Resources

Contact Us

Chair: Zhiwen Zhang
Administrative Assistant: Matthew Blanco

Bioengineering
Santa Clara University
500 El Camino Real
Santa Clara, CA 95053

Discovery and Innovation, Bldg. 402

408-554-4874

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Limited Financial Aid for Current Graduate Students

Please contact your academic advisor regarding openings for:

  • Teaching Assistants (hourly pay + tuition stipend)
  • Graders (hourly pay only)